Somatically acquired oncogene mutational change is fundamental to thyroid neoplasia. While certain mutations confer highly predictable degrees of biological aggressiveness, other mutation types are less predictable. We report on our large experience thyroid nodule mutational change correlated with cytology and RNA expression level determination to better understand neoplastic progression according to specific mutation type.
Clinical and Biological Significance of Common Mutational Genotypes of Thyroid Follicular Neoplasia
Patient management decisions are based on the independent medical judgment of the physician and molecular test results should be taken into consideration in conjunction with all relevant imaging, clinical findings, patient and family history, as well as patient preference.