MicroRNA Profiling Addresses Mutational Heterogeneity in Individual Thyroid Nodules

Acquisition of cancer-associated mutational change is fundamental to thyroid carcinogenesis however up to 30% of thyroid follicular lining cell malignancies can lack detection of mutational change.

Our study uses a combined mutation detection and microRNA (miRNA) classifier determination to evaluate the role of mutational heterogeneity in thyroid nodules.

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